When your body is missing cofactors or enzymes it affects the pathway function. This means your missing the key to making your body to work correctly causing pain, inflammation, anxiety, reactions to foods...find alternative medicine and vitamins and supplements
"Timing is everything," and that is critical for vitamins and supplements. Alternative medicine treatment of symptoms for a single issue will not solve all pathways, in fact it can do more harm than good. We need to address the entire body and the issues in an order that creates a step by step solution. Don't risk taking supplements without guidance and knowledge.
Our categories of nutritional support are targeted to many areas of health and wellness. From our extensive homeopathy line to our pristine ECO glandulars, we are proud to offer a wide range of products that can be used by clinicians for various conditions.
We also are the only company to carry an extensive epigenetic line, MethylGenetic Nutrition®, which supports both lifestyle, diet and stress as well as specific common genetic weaknesses such as MTHFR. Purchase our vitamins and supplements for alternative medicine health benefits.
"I want to make it absolutely clear that while the MTHFR mutation may be common across a number of individuals, the outcome of supplementing with various nutrients can vary tremendously due to other genetic defects, dietary and lifestyle choices and environmental exposures."
Ben Lynch, ND
COMT (catechol-O-methyltransferase) helps break down certain neurotransmitters and catecholamines. These include dopamine, epinephrine, and norepinephrine. Catechol-O-methyltransferase is important to the areas of the pre-frontal cortex. This area of the brain is involved with personality, inhibition of behaviors, short-term memory, and planning. While abstract thinking, and emotion. COMT is also involved with metabolizing estrogens. COMT catalyzes the transfer of the methyl-group from SAM to catecholamine substrates. Like L-DOPA, dopamine, epinephrine and norepinephrine.
COMT individuals can usually break down these neurotransmitters efficiently. But some COMT individuals may have trouble breaking these chemicals down from impaired function of the enzyme. With a positive COMT status, it has been clinically observed by physicians. Those people may have trouble with methyl donors. This can lead to irritability, hyperactivity, or abnormal behavior. They may also be more sensitive to pain. COMT mutations slow the activity of the COMT enzyme which slows dopamine causing dopamine excess of imbalances.
COMT is also important in the detoxification of xenobiotics and metabolism of catechol drugs. COMTV158 is associated with a 3-4 x reduction or increase in activity and increased reaction to heat.
COMT V158M + H62H heterozygous is associated with low or high catecholamines.
V158M + H62H homozygous is associated with high catecholamines and excess estrogen.
In patients with typical symptoms of histamine intolerance that are triggered by histamine-rich food and alcohol, with intolerance of drugs that liberate histamine or block DAO, and with a negative diagnosis of allergy or internal disorders, histamine intolerance should be considered. A histamine-free diet, if necessary, supported by antihistamines or the substitution of DAO, leads to an improvement of symptoms. However, further studies investigating histamine intolerance due to DBPC provocations are indispensable.
Laura Maintz, Natalija Novak
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